John V Count of Nassau-Dietz, 1455-1516, Stadholder of Gelderland
| | | | | | | | | | John IV Prince of Orange, 1475-1502
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| William the Rich Count of Nassau-Dillenburg 1487- 1559
| | | | | | Henry III Count of Nassau-Breda 1483-1538
| | Claudia of Châlon 1498–1521 | | | | | Philibert of Châlon, Prince of Orange, 1502-1530
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| William I "the Silent" 1533-1584, Prince of Orange 1544, Stadholder of Holland, Zealand & Utrecht, assassinated by Spanish agent
| | Louis 1538–1574 died in battle against Spain
| | Adolf 1540–1568, died in battle against Spain
| | Henry 1550-1574 died in battle against Spain
| | John VI "the Elder" 1535–1606, Stadholder of Gelderland
| | | René of Châlon 1519–1544, Prince of Orange,1521
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| Philip William 1554–1618, Prince of Orange, 1584
| | Maurice 1567–1625, Prince of Orange,1618, Stadholder of Holland, Zealand, Utrecht, etc.
| | Frederick Henry 1584–1647, Prince of Orange, 1625, Stadtholder of Holland, Zeeland, & etc.
| | Louise Juliana 1576-1644 married Frederick IV Elector Palatine from whom the British royal family descends | | Elisabeth 1577-1642 married Henri de La Tour d'Auvergne, Duke of Bouillon | | illeg. Justinus van Nassau (1559 – 1631) Admiral & General, Gov of Breda 1601-1625
| | | William Louis "Us Heit", Count of Nassau-Dillenburg 1560–1620, Stadtholder of Friesland, Groningen, and Drenthe
| | Ernst Casimir, Count of Nassau-Dietz 1573–1632, Stadtholder of Friesland, Groningen, and Drenthe
| | | John VII "the Middle", Count of Nassau-Siegen, 1561–1623
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| | | | illeg William of Nassau (1601–1627), lord of de Lek | | illeg Louis of Nassau, Lord of De Lek and Beverweerd (1602– 1665)
| | | | | | Frederick V, Elector Palatine, 1610 & King of Bohemia 1619-21 | | | Henri de la Tour d'Auvergne, Vicomte de Turenne & Marshal-General of France 1611-1675 | | | | | | | | | | | | | | | | | | | |
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| | | | | | Charles I, King of England 1625-1649
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| | | | | | | | | | | Charles II
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| William II 1626-1650,Prince of Orange & Stadholder of Holland, Zealand, etc, 1647
| | Mary,Princess Royal
| James II
| | Louise Henriette (1627-1667) married Frederick William, Elector of Brandenburg descendants were Kings of Prussia and later German Emperors | | illeg. Frederick Nassau de Zuylestein (1608–1672) general of the army, descendants were the Earls of Rochford in England
| | | Albertine Agnes(1634– 1696) | | | | William Frederick,1613-1664 Count later Prince of Nassau-Dietz,Stadtholder of Friesland, Groningen and Drenthe
| | | | Henry Casimir I Count of Nassau-Dietz,1612–1640,Stadtholder of Friesland, Groningen and Drenthe
| | John Maurice "the Brazilian", Prince of Nassau-Siegen,1604–1679,gov. of Dutch Brazil, Field Marshal of the Dutch Army
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| | | William III 1650-1702,Prince of Orange 1650, Stadholder of Holland, Zealand, etc, 1672, King of England, 1689
| | Mary II of England
| | | ceded claims to the lands of Orange to France in 1713, but kept right to use the title in its German form: currently Georg Friedrich, Prince of Prussia, "Prinz von Oranien" | | | | | | | | | Henry Casimir II, Prince of Nassau-Dietz,1657-1696,Stadtholder of Friesland, Groningen and Drenthe
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| | | | | | | | | | | | | | | | | | John William Friso 1687-1711, appointed heir by William III, Prince of Orange, 1702, Stadholder of Friesland 1696
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| | | | | | | | | | | | | | Anne, Princess Royal of England | | William IV 1711–1751, Prince of Orange, Stadholder of Holland, Zealand, etc. 1747
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| | | | | | | | | | | | | | Wilhelmina of Prussia | | William V 1748–1806, Prince of Orange,1751 Stadholder of Holland, Zealand, etc. 1751-1795
| | | Carolina 1743–1787 | | Charles Christian, Prince of Nassau-Weilburg, 1735-1788 | | | | | | |
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| | | | | | | | Princess Louise of Orange-Nassau, 1770– 1819 married Karl, Hereditary Prince of Braunschweig(-Wolfenbuttel), son of Princess Augusta of Great Britain | | Prince Frederick of Orange-Nassau, 1774–1799 an Austrian General, no issue | | William VI, Fürst of Nassau-Orange-Fulda 1803–1806, Fürst of Nassau-Orange, Prince of Orange 1806 later William I, King of the Netherlands 1815
| | | | | | | Frederick William, Prince of Nassau-Weilburg, 1768-1816 | | | | |
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| | | | | | | | | | | | | | | | Royal Family of the Netherlands, see next table below | | | | | | | William, Duke of Nassau, 1792-1839 | | |
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| | | | | | | | | | | | | | | | | | | | | | | | | Adolphe 1817–1905, Duke of Nassau 1839-1866,Grand Duke of Luxembourg, 1890-1905 |
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| | | | | | | | | | | | | | | | | | | | | | | | | Grand Ducal Family of Luxembourg |