Fallypride (18F)
Clinical data
  • N/A
ATC code none
Legal status
Legal status
  • Research compound
PubChem (CID) 10021692
ChemSpider 8197265
Chemical and physical data
Formula C20H29FN2O3
Molar mass 364.454263 g/mol
3D model (Jmol) Interactive image

Fallypride is a high affinity dopamine D2/D3 receptor antagonist used in medical research,[1] [2] usually in the form of fallypride (18F) as a positron emission tomography (PET) radiotracer in human studies.[3][4]


  1. Mukherjee, J; Yang, Z. Y.; Das, M. K.; Brown, T (1995). "Fluorinated benzamide neuroleptics--III. Development of (S)-N-(1-allyl-2-pyrrolidinyl)methyl-5-(3-18Ffluoropropyl)-2, 3-dimethoxybenzamide as an improved dopamine D-2 receptor tracer". Nuclear Medicine and Biology. 22 (3): 283–96. PMID 7627142.
  2. Template:Pmid = 26422464
  3. Mukherjee, J; Christian, B. T.; Dunigan, K. A.; Shi, B; Narayanan, T. K.; Satter, M; Mantil, J (2002). "Brain imaging of 18F-fallypride in normal volunteers: Blood analysis, distribution, test-retest studies, and preliminary assessment of sensitivity to aging effects on dopamine D-2/D-3 receptors". Synapse. 46 (3): 170–88. doi:10.1002/syn.10128. PMID 12325044.
  4. Rieck, R. W.; Ansari, M. S.; Whetsell Jr, W. O.; Deutch, A. Y.; Kessler, R. M. (2004). "Distribution of dopamine D2-like receptors in the human thalamus: Autoradiographic and PET studies". Neuropsychopharmacology. 29 (2): 362–72. doi:10.1038/sj.npp.1300336. PMID 14627996.

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