Legal status
Legal status
CAS Number 1883284-94-3
PubChem (CID) 119025888
ChemSpider 29763739
UNII 85E88884ZQ YesY
Chemical and physical data
Formula C26H18FNO2
Molar mass 395.42 g/mol
3D model (Jmol) Interactive image

FDU-PB-22 is an derivative of JWH-018 that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a "legal high".[1][2]


FDU-PB-22 acts as a full agonist with a binding affinity of 1.19nM at CB1 and 2.43nM at CB2 cannabinoid receptors.[3]

FDU-PB-22 is a controlled substance in Germany and is banned in Japan and Sweden.[4]

See also


  1. "FDU-PB-22". Southern Association of Forensic Scientists. Retrieved 23 July 2015.
  2. Uchiyama, Nahoko; Shimokawa, Yoshihiko; Kikura-Hanajiri, Ruri; Demizu, Yosuke; Goda, Yukihiro; Hakamatsuka, Takashi (1 July 2015). "A synthetic cannabinoid FDU-NNEI, two 2H-indazole isomers of synthetic cannabinoids AB-CHMINACA and NNEI indazole analog (MN-18), a phenethylamine derivative N–OH-EDMA, and a cathinone derivative dimethoxy-α-PHP, newly identified in illegal products". Forensic Toxicology. 33 (2): 244–259. doi:10.1007/s11419-015-0268-7. ISSN 1860-8965. PMC 4525202Freely accessible. PMID 26257833.
  3. Hess, Cornelius; Schoeder, ClaraT.; Pillaiyar, Thanigaimalai; Madea, Burkhard; Müller, ChristaE. (1 July 2016). "Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice". Forensic Toxicology. 34 (2): 329–343. doi:10.1007/s11419-016-0320-2. ISSN 1860-8965. PMC 4929166Freely accessible. PMID 27429655.
  4. "Cannabinoider föreslås bli klassificerade som hälsofarlig vara". Folkhälsomyndigheten. 28 May 2014. Retrieved 23 July 2015.

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