Space-filling model of the etofibrate molecule
Clinical data
AHFS/ International Drug Names
ATC code C10AB09 (WHO)
Pharmacokinetic data
Metabolism Hydrolyzed to clofibric acid and niacin
CAS Number 31637-97-5 YesY
PubChem (CID) 65777
DrugBank DB08983 YesY
ChemSpider 59197 YesY
UNII 23TF67G79M YesY
KEGG D07187 YesY
ECHA InfoCard 100.046.115
Chemical and physical data
Formula C18H18ClNO5
Molar mass 363.792 g/mol
3D model (Jmol) Interactive image

Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.[1]


  1. Sposito AC, Mansur AP, Maranhão RC, Rodrigues-Sobrinho CR, Coelho OR, Ramires JA (2001). "Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects". Braz J Med Biol Res. 34 (2): 177–82. doi:10.1590/S0100-879X2001000200004. PMID 11175492. Free full text

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