EMP3

EMP3

Identifiers

EMP3, YMP, epithelial membrane protein 3

External IDs

MGI: 1098729 HomoloGene: 1090 GeneCards: EMP3

Gene ontology
Molecular function	• protein binding
Cellular component	• integral component of membrane • plasma membrane • membrane
Biological process	• cell growth • bleb assembly • cell death • negative regulation of cell proliferation
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


2014


13732


ENSG00000142227


ENSMUSG00000040212


P54852


O35912

RefSeq (mRNA)


NM_001313905 NM_001425


NM_001146346 NM_010129

RefSeq (protein)


NP_001416.1 NP_001300834.1


NP_001139818.1 NP_034259.2

Location (UCSC)

Chr 19: 48.32 – 48.33 Mb

Chr 7: 45.92 – 45.92 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Epithelial membrane protein 3 is a protein that in humans is encoded by the EMP3 gene.^[3]^[4]^[5]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Ben-Porath I, Benvenisty N (Feb 1997). "Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins". Gene. 183 (1–2): 69–75. doi:10.1016/S0378-1119(96)00475-1. PMID 8996089.
↑ Liehr T, Kuhlenbaumer G, Wulf P, Taylor V, Suter U, Van Broeckhoven C, Lupski JR, Claussen U, Rautenstrauss B (Jul 1999). "Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3". Genomics. 58 (1): 106–8. doi:10.1006/geno.1999.5803. PMID 10331954.
↑ "Entrez Gene: EMP3 epithelial membrane protein 3".

Further reading

Lobsiger CS, Magyar JP, Taylor V, et al. (1997). "Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1". Genomics. 36 (3): 379–87. doi:10.1006/geno.1996.0482. PMID 8884260.
Taylor V, Suter U (1996). "Epithelial membrane protein-2 and epithelial membrane protein-3: two novel members of the peripheral myelin protein 22 gene family". Gene. 175 (1–2): 115–20. doi:10.1016/0378-1119(96)00134-5. PMID 8917086.
Bolin LM, McNeil T, Lucian LA, et al. (1997). "HNMP-1: a novel hematopoietic and neural membrane protein differentially regulated in neural development and injury". J. Neurosci. 17 (14): 5493–502. PMID 9204931.
Yus-Najera E, Santana-Castro I, Villarroel A (2002). "The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels". J. Biol. Chem. 277 (32): 28545–53. doi:10.1074/jbc.M204130200. PMID 12032157.
Wilson HL, Wilson SA, Surprenant A, North RA (2002). "Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus". J. Biol. Chem. 277 (37): 34017–23. doi:10.1074/jbc.M205120200. PMID 12107182.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Schwake M, Jentsch TJ, Friedrich T (2003). "A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly". EMBO Rep. 4 (1): 76–81. doi:10.1038/sj.embor.embor715. PMC 1315815. PMID 12524525.
Yus-Nájera E, Muñoz A, Salvador N, et al. (2003). "Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation". Neuroscience. 120 (2): 353–64. doi:10.1016/S0306-4522(03)00321-X. PMID 12890507.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Nielsen K, Heegaard S, Vorum H, et al. (2005). "Altered expression of CLC, DSG3, EMP3, S100A2, and SLPI in corneal epithelium from keratoconus patients". Cornea. 24 (6): 661–8. doi:10.1097/01.ico.0000153556.59407.69. PMID 16015083.
Li KK, Pang JC, Chung NY, et al. (2007). "EMP3 overexpression is associated with oligodendroglial tumors retaining chromosome arms 1p and 19q". Int. J. Cancer. 120 (4): 947–50. doi:10.1002/ijc.22415. PMID 17187361.
Kunitz A, Wolter M, van den Boom J, et al. (2007). "DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas". Brain Pathol. 17 (4): 363–70. doi:10.1111/j.1750-3639.2007.00083.x. PMID 17610521.

This article is issued from Wikipedia - version of the 6/6/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.