Eoxin A4

Eoxin A4
Names

IUPAC name (5Z,8Z,10E,12E)-13-[(2S,3S)-3-Pentyl-2-oxiranyl]-5,8,10,12-tridecatetraenoic acid
Other names EXa4; 14,15-LTA4
Identifiers
3D model (Jmol)	Interactive image
ChEBI	CHEBI:63983
ChemSpider	27471348
PubChem	52921883
InChI InChI=1S/C20H30O3/c1-2-3-12-15-18-19(23-18)16-13-10-8-6-4-5-7-9-11-14-17-20(21)22/h4,6-10,13,16,18-19H,2-3,5,11-12,14-15,17H2,1H3,(H,21,22)/b6-4-,9-7-,10-8+,16-13+/t18-,19-/m0/s1 Key: URDQSJSEGRMOIT-FDMWOPBLSA-N
SMILES CCCCC[C@H]1[C@@H](O1)/C=C/C=C/C=C\C/C=C\CCCC(=O)O
Properties
Chemical formula	C₂₀H₃₀O₃
Molar mass	318.46 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Eoxin A4, also known as 14,15-leukotriene A4, is an eoxin.

Leukotriene C4 synthase (aka glutathione S-transferase II) converts it to eoxin C4.

Precursor

Precursor

Active

D/J	D₂

E/F	E₂ (Dinoprostone) E₁ (Alprostadil) F_2α (Dinoprost):

I	I₂ (Prostacyclin/Epoprostenol):

Precursor	Arachidonic acid 5-hydroperoxide

Initial	A₄ B₄

SRS-A	C₄ D₄ E₄

Precursor	Arachidonic acid 15-hydroperoxide

Eoxins	A₄ C₄ D₄ E₄

By function

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