EMPA (drug)

Clinical data
ATC code none
CAS Number 680590-49-2
PubChem (CID) 9981404
ChemSpider 8156996
ECHA InfoCard 100.233.393
Chemical and physical data
Formula C23H26N4O4S
Molar mass 454.542 g/mol
3D model (Jmol) Interactive image

EMPA is a selective antagonist of the OX2 receptor, with 900-fold selectivity in binding for OX2 over OX1.[1][2]

See also


  1. "Biochemical and Electrophysiological Characterization of Almorexant, a Dual Orexin 1 Receptor (OX1)/Orexin 2 Receptor (OX2) Antagonist: Comparison with Selective OX1 and OX2 Antagonists", , Pari Malherbe, Edilio Borroni, Emmanuel Pinard, Joseph G. Wettstein, and Frederic Knoflach, in Molecular Pharmacology, , 2009
  2. Malherbe et al (2009) Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX2 receptor. Br.J.Pharmacol. 156 1326. PMID 19751316.

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