Difetarsone
 | |
 | |
| Clinical data | |
|---|---|
| ATC code | P01AR02 (WHO) QP51AD02 (WHO) |
| Identifiers | |
| |
| CAS Number | 3639-19-8 |
| PubChem (CID) | 68199 |
| ChemSpider | 61506 |
| UNII |
G4G9J3Q65W  |
| KEGG | D07357 |
| ECHA InfoCard | 100.020.788 |
| Chemical and physical data | |
| Formula | C14H18As2N2O6 |
| Molar mass | 460.146 g/mol |
Difetarsone is an antiprotozoal agent. Various studies have shown it to be particularly effective against Trichuris trichiura, commonly known as the whipworm. Prior to the drugs use in the early 1970s, there were few effective treatments for this infection.[1] It has also been used to treat Entamoeba histolytica infections.[2]
Difetarsone often has minor side effects, which include rashes, nausea and vomiting. It has also resulted in angioedema in at least one known case.[2]
References
- ↑ P.M. Leary; C. Jones; F. Douglas; S.T. Boyd (June 1972). "Difetarsone in Difetarsone in outpatient treatment of Trichuris trichiura infestation". Archives of Disease in Childhood. 49 (6): 486–8. doi:10.1136/adc.49.6.486. PMC 1648795
. PMID 4851370. - 1 2 Jeffrey K. Aronson (2009). Meyler's Side Effects of Antimicrobial Drugs. p. 834. ISBN 9780080932934. Retrieved October 7, 2013.
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