Clinical data
AHFS/ International Drug Names
ATC code N04AA08 (WHO)
CAS Number 21888-98-2 N
PubChem (CID) 30843
DrugBank DB08997 N
ChemSpider 28615 YesY
UNII 43477QYX3D YesY
KEGG D03711 YesY
Chemical and physical data
Formula C23H26N2O2
Molar mass 362.465 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Dexetimide (brand name Tremblex) is a piperidine anticholinergic. It is a muscarinic antagonist that is used to treat drug induced parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968.[1][2]


  1. Dom, R.; Van Lommel, R.; Baro, F. (1971). "A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent". Acta Psychiatrica Scandinavica. 47 (4): 399–410. doi:10.1111/j.1600-0447.1971.tb03697.x. PMID 4947805.
  2. Huygens, H.; Vereecken, J. L.; Tanghe, A. (1973). "Dexetimide (R 16470) in the control of neuroleptic-induced extrapyramidal side-effects. Its prophylactic value and duration of action". Psychiatria, neurologia, neurochirurgia. 76 (4): 251–259. PMID 4581374.

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