Legal status
Legal status
Synonyms 2,5-Dimethoxy-4-propylamphetamine
CAS Number 63779-88-4 N
53581-55-8 (hydrochloride)
PubChem (CID) 542051
ChemSpider 472021 YesY
Chemical and physical data
Formula C14H23NO2
Molar mass 237.34 g/mol
3D model (Jmol) Interactive image
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2,5-Dimethoxy-4-propylamphetamine (DOPR) is a psychedelic drug of the phenethylamine and amphetamine chemical classes. It was first synthesized by Alexander Shulgin, and was described in his book PiHKAL (Phenethylamines i Have Known And Loved). Shulgin described DOPR is a "heavy duty psychedelic", complete with alterations of the thought process and visual distortion.[1] Very little data exists about the pharmacological properties, metabolism, and toxicity of DOPR.

The alternative structural isomer DOIP, with a 4-isopropyl substitution, is also known but is around ten times weaker than DOPR, with an active dose of some 20-30 mg (as compared to 2-5 mg for DOPR).[1]

Structure of DOIP

See also


  1. 1 2 Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. United States: Transform Press. p. 978. ISBN 0-9630096-0-5.

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