Chromosome 11 (human)

Chromosome 11 (human)

Pair of human chromosome 11 (after G-banding).
One is from mother, one is from father.

Chromosome 11 pair in human male karyogram.
Length (bp) 135,086,622 bp
Number of genes 2,364
Type Autosome
Centromere position Submetacentric[1]
RefSeq NC_000011
GenBank CM000673
Map of Chromosome 11
Ideogram of human chromosome 11. Mbp means mega base pair. See locus for other notation.

Chromosome 11 is one of the 23 pairs of chromosomes in humans. Humans normally have two copies of this chromosome. Chromosome 11 spans about 135 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells. It is one of the most gene- and disease-rich chromosomes in the human genome.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 11 likely contains between 1,300 and 1,700 genes.

A recent study [2] shows that 11.6 genes per megabase, including 1,524 protein-coding genes and 765 pseudogenes can be found on chromosome 11.

More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single- and multi-gene clusters along this chromosome.


The following are some of the genes located on chromosome 11:

Diseases and disorders

Wikinews has related news: Large study provides new insights in autism's genetic code

The following diseases and disorders are some of those related to genes on chromosome 11:


  1. "Table 2.3: Human chromosome groups". Human Molecular Genetics (2nd ed.). Garland Science. 1999.
  2. Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E, Chang JL, Cuomo CA, Eichler E, FitzGerald MG, Jaffe DB, LaButti K, Nicol R, Park HS, Seaman C, Sougnez C, Yang X, Zimmer AR, Zody MC, Birren BW, Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES, Sakaki Y (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. doi:10.1038/nature04632. PMID 16554811.
  3. INS - insulin - Genetics Home Reference
  4. "Autism gene breakthrough hailed". Health. BBC NEWS. 2007-02-19. Retrieved 2010-01-02.
  5. Human Genome Project Information Site Has Been Updated
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