Charles Yanofsky

Charles Yanofsky
Born (1925-04-17) April 17, 1925
New York
Nationality United States
Fields Genetics
Institutions Stanford University
Alma mater City College of New York
Yale University (Ph.D, 1951)
Notable awards National Medal of Science (2003)
Passano Award (1992)
Thomas Hunt Morgan Medal (1990)
Genetics Society of America Medal (1983)
Louisa Gross Horwitz Prize (1976)
Selman A. Waksman Award in Microbiology (1972)
Albert Lasker Award (1971)
NAS Award in Molecular Biology (1964)

Charles Yanofsky (born April 17, 1925) is a leading American geneticist.

Born in New York, Yanofsky studied at the City College of New York and at Yale University.

In 1964, Yanofsky and colleagues established that gene sequences and protein sequences are colinear in bacteria.[1] Yanofsky showed that changes in DNA sequence can produce changes in protein sequence at corresponding positions.[2] His work revealed how controlled alterations in RNA structure allow RNA to serve as a regulatory molecule in both bacterial and animal cells.

Yanofsky was awarded the Selman A. Waksman Award in Microbiology from the National Academy of Sciences in 1972[3] and was co-recipient of the Louisa Gross Horwitz Prize from Columbia University in 1976 with Seymour Benzer. Yanofsky was elected a foreign member of the Royal Society in 1985 and was one of the recipients of the 2003 National Medal of Science awards.

Charles Yanofsky is now the Morris Herzstein Professor of Biology and Molecular Biology (Emeritus) in the Department of Biology at Stanford University.



  1. Yanofsky, Charles; Carlton, B. C.; Guest, J. R.; Helinski, D. R.; Henning, U. (Dec 18, 1963). "ON THE COLINEARITY OF GENE STRUCTURE AND PROTEIN STRUCTURE". Proc Natl Acad Sci U S A. 51 (2): 266–272. doi:10.1073/pnas.51.2.266. PMC 300060Freely accessible. PMID 14124325.
  2. Yanofsky, C.; Drapeau, G. R.; Guest, J. R.; Carlton, B. C. (1967). "THE COMPLETE AMINO ACID SEQUENCE OF THE TRYPTOPHAN SYNTHETASE a PROTEIN (alpha SUBUNIT) AND ITS COLINEAR RELATIONSHIP WITH THE GENETIC MAP OF THE a GENE". Proceedings of the National Academy of Sciences of the United States of America. 57 (2): 296–298. doi:10.1073/pnas.57.2.296. PMC 335504Freely accessible. PMID 16591468.
  3. "Selman A. Waksman Award in Microbiology". National Academy of Sciences. Retrieved 15 February 2011.

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