Cen Hun (died 280) was a minister under Eastern Wu during the later years of the Three Kingdoms Period of China. He was a close friend of Wu's last emperor, Sun Hao.
In the historical novel Romance of the Three Kingdoms, Cen Hun was made into an eunuch, and was credited with inciting Sun Hao's tyranny, and considered one of the two most corrupt and useless officials taking significant responsibilities in the elimination of Shu Han and Eastern Wu, the other being Shu's Huang Hao. Following the surrender of Wu to Jin, many subjects under the fallen state cried out "Cen Hun is to blame for everything!". He was then executed by slow slicing.