CCDC50

CCDC50

Identifiers

CCDC50, C3orf6, DFNA44, YMER, coiled-coil domain containing 50

External IDs

HomoloGene: 32655 GeneCards: CCDC50

Gene ontology
Molecular function	• protein binding • ubiquitin protein ligase binding
Cellular component	• cytoplasm • microtubule
Biological process	• sensory perception of sound
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


152137


n/a


ENSG00000152492


n/a


Q8IVM0


n/a

RefSeq (mRNA)


NM_174908 NM_178335


n/a

RefSeq (protein)


NP_777568.1 NP_848018.1


n/a

Location (UCSC)

Chr 3: 191.33 – 191.4 Mb

n/a

PubMed search

^[1]

n/a

View/Edit Human

Coiled-coil domain-containing protein 50 is a protein that in humans is encoded by the CCDC50 gene.^[2]^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ Vazza G, Picelli S, Bozzato A, Mostacciuolo ML (Oct 2003). "Identification and characterization of C3orf6, a new conserved human gene mapping to chromosome 3q28". Gene. 314: 113–20. doi:10.1016/S0378-1119(03)00710-8. PMID 14527723.
↑ Tashiro K, Konishi H, Sano E, Nabeshi H, Yamauchi E, Taniguchi H (Aug 2006). "Suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by Ymer, a novel tyrosine-phosphorylated and ubiquitinated protein". J Biol Chem. 281 (34): 24612–22. doi:10.1074/jbc.M604184200. PMID 16803894.
↑ "Entrez Gene: CCDC50 coiled-coil domain containing 50".

Further reading

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Modamio-Høybjør S, Moreno-Pelayo MA, Mencía A, et al. (2003). "A novel locus for autosomal dominant nonsyndromic hearing loss (DFNA44) maps to chromosome 3q28-29.". Hum. Genet. 112 (1): 24–8. doi:10.1007/s00439-002-0836-x. PMID 12483295.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Blagoev B, Ong SE, Kratchmarova I, Mann M (2005). "Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics.". Nat. Biotechnol. 22 (9): 1139–45. doi:10.1038/nbt1005. PMID 15314609.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.". Mol. Cell Proteomics. 4 (9): 1240–50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Modamio-Hoybjor S, Mencia A, Goodyear R, et al. (2007). "A mutation in CCDC50, a gene encoding an effector of epidermal growth factor-mediated cell signaling, causes progressive hearing loss.". Am. J. Hum. Genet. 80 (6): 1076–89. doi:10.1086/518311. PMC 1867096. PMID 17503326.

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