Beta1-adrenergic agonists, also known as Beta1-adrenergic receptor agonists, are a class of drugs that bind selectively to the beta-1 adrenergic receptor. As a result, they act more selectively upon the heart. Beta-adrenoceptors typically bind to norepinephrine release by sympathetic adrenergic nerves and to circulating epinephrine. The effect of B-adrenoceptors is cardiac stimulation, such as increased heart rate, contractility, conduction velocity and relaxation.
- Sakuma T, Hida M, Nambu Y, et al. (February 2001). "Beta1-adrenergic agonist is a potent stimulator of alveolar fluid clearance in hyperoxic rat lungs". Jpn. J. Pharmacol. 85 (2): 161–6. doi:10.1254/jjp.85.161. PMID 11286398.
- Nishio R, Matsumori A, Shioi T, et al. (September 1998). "Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart". J. Am. Coll. Cardiol. 32 (3): 808–15. doi:10.1016/S0735-1097(98)00314-3. PMID 9741531.