Epicriptine

Main article: Dihydroergocryptine
Epicriptine
Clinical data
Pregnancy
category
  • Contraindicated
Routes of
administration
Oral
ATC code N04BC03 (WHO) (alpha/beta)
Legal status
Legal status
  • ℞ (Prescription only)
Identifiers
Synonyms beta-Dihydroergocryptine
CAS Number 19467-62-0
PubChem (CID) 3084313
ChemSpider 2341400
UNII 5M64643B5U
ChEBI CHEBI:59925
ChEMBL CHEMBL1378681
ECHA InfoCard 100.039.157
Chemical and physical data
Formula C32H43N5O5
Molar mass 577.715 g/mol
3D model (Jmol) Interactive image

Epicriptine or beta-dihydroergocryptine is a dopamine agonist of the ergoline class. It constitutes one third of the mixture known as dihydroergocryptine, the other two thirds consisting of alpha-dihydroergocryptine. The alpha differs from the beta form only in the position of a single methyl group, which is a consequence of the biosynthesis in which the proteinogenic amino acid isoleucine is replaced by leucine.[1]

References

  1. Steinhilber, D; Schubert-Zsilavecz, M; Roth, HJ (2005). Medizinische Chemie (in German). Stuttgart: Deutscher Apotheker Verlag. p. 142. ISBN 3-7692-3483-9.



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