Benadryl is a brand name for a number of different medications. In the United States and Canada, it is the first-generation antihistamine diphenhydramine. In the United Kingdom, it is either the antihistamine acrivastine (marketed as Benadryl Allergy Relief) or the long-acting antihistamine cetirizine (marketed as Benadryl One a Day Relief). Some Benadryl products marketed in Australia and New Zealand as a cough medicine contain diphenhydramine.[1]

Benadryl is available for by mouth or topical use. It is marketed without a prescription by Johnson & Johnson subsidiary McNeil Consumer Healthcare. Before 2007, Benadryl was marketed by Pfizer Consumer Healthcare.[2][3] Benadryl Chesty Cough & Nasal Congestion contains guaifenesin (an expectorant) and pseudoephedrine hydrochloride as the active ingredients.[4]


  1. "ARTG, PI and CMI results searching for Benadryl". Department of Health Therapeutic Goods Administration, Australia.
  2. "Johnson & Johnson to Acquire Pfizer Consumer Healthcare" (Press release). Johnson & Johnson. June 26, 2006. Retrieved November 19, 2009.
  3. "Johnson & Johnson Completes Acquisition Of Pfizer Consumer Healthcare" (Press release). Johnson & Johnson. December 20, 2006. Retrieved November 19, 2009.
  4. Benadryl for the Family Chesty Cough & Nasal Congestion Oral Liquid ; accessed Oct. 13, 2011

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