Acotiamide

Acotiamide
Clinical data
Routes of
administration
Oral
ATC code none
Legal status
Legal status
  • Uncontrolled
Identifiers
CAS Number 185106-16-5 N
PubChem (CID) 5282338
ChemSpider 4445505 YesY
UNII D42OWK5383 YesY
ChEMBL CHEMBL2107723 N
Chemical and physical data
Formula C21H30N4O5S
Molar mass 450.55 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Acotiamide (YM-443, Z-338) is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia.[1] It acts as an acetylcholinesterase inhibitor.

References

  1. Matsueda K, Hongo M, Tack J, Aoki H, Saito Y, Kato H (January 2010). "Clinical trial: dose-dependent therapeutic efficacy of acotiamide hydrochloride (Z-338) in patients with functional dyspepsia - 100 mg t.i.d. is an optimal dosage". Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22 (6): 618–e173. doi:10.1111/j.1365-2982.2009.01449.x. PMID 20059698.
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