ALDH1L2

ALDH1L2
Identifiers
Aliases ALDH1L2, mtFDH, aldehyde dehydrogenase 1 family member L2
External IDs MGI: 2444680 HomoloGene: 51942 GeneCards: ALDH1L2
Orthologs
Species Human Mouse
Entrez

160428

216188

Ensembl

ENSG00000136010

ENSMUSG00000020256

UniProt

Q3SY69

Q8K009

RefSeq (mRNA)

NM_001034173

NM_153543

RefSeq (protein)

NP_001029345.2

NP_705771.2

Location (UCSC) Chr 12: 105.02 – 105.08 Mb Chr 10: 83.49 – 83.53 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Aldehyde dehydrogenase 1 family, member L2 also known as ALDH1L2 is an enzyme that in humans is encoded by the ALDH1L2 gene.[3][4] ALDH1L2 is the mitochondrial isoform of a similar enzyme, ALDH1L1, which converts 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide.[5][6]

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ "Mouse PubMed Reference:".
  3. ↑ Strausberg RL, Feingold EA, Grouse LH, et al. (December 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241Freely accessible. PMID 12477932.
  4. ↑ Ota T, Suzuki Y, Nishikawa T, et al. (January 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  5. ↑ Krupenko NI, Dubard ME, Strickland KC, Moxley KM, Oleinik NV, Krupenko SA. "ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase." J Biol Chem. 2010 Jul 23;285(30):23056-63.
  6. ↑ Strickland KC, Krupenko NI, Dubard ME, Hu CJ, Tsybovsky Y, Krupenko SA. "Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahdyrofolate dehydrogenase." Chem Biol Interact. 2011 May 30;191(1-3):129-36.

Further reading


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