Skeletal formula of 8-CPT
Ball-and-stick model of the 8-CPT molecule
Clinical data
ATC code none
Legal status
Legal status
  • Uncontrolled
CAS Number 35873-49-5 YesY
PubChem (CID) 1917
ChemSpider 1843 YesY
Chemical and physical data
Formula C12H16N4O2
Molar mass 248.280 g/mol
3D model (Jmol) Interactive image

8-Cyclopentyl-1,3-dimethylxanthine (8-Cyclopentyltheophylline, 8-CPT, CPX) is a drug which acts as a potent and selective antagonist for the adenosine receptors, with some selectivity for the A1 receptor subtype, as well as a non-selective phosphodiesterase inhibitor. It has stimulant effects in animals with slightly higher potency than caffeine.[1][2]

See also


  1. Spealman RD (1988). "Psychomotor stimulant effects of methylxanthines in squirrel monkeys: relation to adenosine antagonism". Psychopharmacology. 95 (1): 19–24. doi:10.1007/bf00212759. PMID 3133696.
  2. Karcz-Kubicha M; Antoniou K; Terasmaa A; Quarta D; Solinas M; Justinova Z; Pezzola A; Reggio R; Müller CE; Fuxe K; Goldberg SR; Popoli P; Ferré S (July 2003). "Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration". Neuropsychopharmacology. 28 (7): 1281–91. doi:10.1038/sj.npp.1300167. PMID 12700682.

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