Clinical data
Routes of
Legal status
Legal status
CAS Number 22196-72-1
PubChem (CID) 30999
ChemSpider 28759
Chemical and physical data
Formula C11H14N2
Molar mass 174.24 g/mol
3D model (Jmol) Interactive image

6-(2-Aminopropyl)indole (6-API, 6-IT) is an indole derivative with no history of use in humans. The analogue 5-API is known to be psychoactive, indicating 6-API may also be psychoactive by the same structure-activity relationship that links 5-APB and 6-APB.

Alexander Shulgin says in his book TiHKAL "From the normal 3-position to the 2, the 4, the 5, the 6 or the 7-positions. All five alpha-methyltryptamine isomers are known, but only one is known to be active in man as a CNS active material. This is the 5-isomer, 5-(2-aminopropyl)indole or 5-IT".

Studies in dogs have also shown the drug to increase hemoglobin levels in the bloodstream.[1]



  1. Maxwell, G. M. (1964). "The effects of an indole derivative 6-(2′-Aminopropyl indole) on the general and coronary haemodynamics of the intact dog". Cellular and Molecular Life Sciences. 20 (9): 526–527. doi:10.1007/BF02154095.
  2. "Temporary class drug order report on 5-6APB and NBOMe compounds". UK Home Office. 4 Jun 2013. Retrieved 2013-07-11.
  3. UK Home Office (2014-03-05). "The Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014". UK Government. Retrieved 2014-03-11.
  4. "Criminal Code Act 1995" (PDF). Australian Government. 2009-08-05. Retrieved 2012-02-08. PAGE 503

This article is issued from Wikipedia - version of the 9/2/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.