5-phosphonooxy-L-lysine phospho-lyase
| 5-phosphonooxy-L-lysine phospho-lyase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.134 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
5-phosphonooxy-L-lysine phospho-lyase (EC 4.2.3.134, 5-phosphohydroxy-L-lysine ammoniophospholyase, AGXT2L2 (gene)) is an enzyme with systematic name (5R)-5-phosphonooxy-L-lysine phosphate-lyase (deaminating; (S)-2-amino-6-oxohexanoate-forming).[1][2] This enzyme catalyses the following chemical reaction
- (5R)-5-phosphonooxy-L-lysine + H2O (S)-2-amino-6-oxohexanoate + NH3 + phosphate
This enzyme is a pyridoxal-phosphate protein.
References
- ↑ Tsai, C.H.; Henderson, L.M. (1974). "Degradation of O-phosphohydroxylysine by rat liver. Purification of the phospho-lyase". J. Biol. Chem. 249: 5784–5789. PMID 4412716.
- ↑ Veiga-da-Cunha, M.; Hadi, F.; Balligand, T.; Stroobant, V.; Van Schaftingen, E. (2012). "Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine". J. Biol. Chem. 287: 7246–7255. doi:10.1074/jbc.m111.323485. PMID 22241472.
External links
- 5-phosphonooxy-L-lysine phospho-lyase at the US National Library of Medicine Medical Subject Headings (MeSH)
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