5'-Methoxyhydnocarpin

5'-Methoxyhydnocarpin
Names
IUPAC name
5,7-Dihydroxy-2-[(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-methoxy-2,3-dihydro-1,4-benzodioxin-7-yl]chromen-4-one
Other names
5′-MHC
Identifiers
3D model (Jmol) Interactive image
ChemSpider 4445172
KEGG C11162
PubChem 5281879
Properties
C26H22O10
Molar mass 494.45 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

5'-Methoxyhydnocarpin (5′-MHC) is a chemical compound that has been isolated from Berberis[1] and Hydnocarpus wightianus.[2]

5′-MHC potentiates the antimicrobial effect of berberine in vitro.[1]

References

  1. 1 2 Stermitz, F. R.; Lorenz, P; Tawara, J. N.; Zenewicz, L. A.; Lewis, K. (February 15, 2000). "Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor". Proceedings of the National Academy of Sciences. National Academy of Sciences. 97 (4): 1433–1437. Bibcode:2000PNAS...97.1433S. doi:10.1073/pnas.030540597. ISSN 1091-6490. PMC 26451Freely accessible. PMID 10677479.
  2. Williams, Cheryll (2013). Medicinal Plants in Australia Volume 4: An Antipodean Apothecary. Rosenberg Publishing. p. 171. ISBN 9781925078084.


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