3-Hydroxyaspartic acid

3-Hydroxyaspartic acid
IUPAC name
3-Hydroxyaspartic acid
Other names
Beta-hydroxyaspartic acid
1860-87-3 N
3D model (Jmol) Interactive image
Interactive image
ChEBI CHEBI:10696 YesY
ChemSpider 391503 YesY
KEGG C11511 YesY
PubChem 443239
Molar mass 149.10 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

3-Hydroxyaspartic acid (three letter abbreviation: Hya) also known as beta-hydroxyaspartic acid is derivative of aspartic acid which has been hydroxylated at position-3. The image to the right shows L-threo-3-Hydroxyaspartate. The Hya amino acid residue is sometimes contained in EGF-like domains such as Vitamin K-dependent coagulation plasma proteins including protein C.[1]


  1. Castellino FJ, Ploplis VA, Zhang L (2008). "gamma-Glutamate and beta-hydroxyaspartate in proteins". Methods Mol. Biol. 446: 85–94. doi:10.1007/978-1-60327-084-7_6. PMID 18373251.

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