Clinical data
ATC code none
Legal status
Legal status
PubChem (CID) 57458869
Chemical and physical data
Formula C11H16FN
Molar mass 181.25 g·mol−1
3D model (Jmol) Interactive image

3-Fluoroethamphetamine (3-FEA) is a stimulant drug of the amphetamine class which acts as a releasing agent of the monoamine neurotransmitters norepinephrine, dopamine and serotonin.

Compared to the unsubstituted ethylamphetamine, 3-fluoroethamphetamine is a weaker releaser of noradrenaline, but a stronger releaser of both dopamine and serotonin, and produced the strongest reinforcing effects in animal studies out of a range of 3-substituted ethamphetamine derivatives tested, despite not being the most potent dopamine releaser.[1][2][3][4]

See also


  1. Tessel RE, Woods JH. Structural relationship between meta-substituted N-ethylamphetamines and self-administration in rhesus monkeys. Pharmacologist 1974;16:142.
  2. Tessel RE; Woods JH; Counsell RE; Lu M (February 1975). "Structure-activity relationships between meta-substituted N-ethylamphetamines and locomotor activity in mice". The Journal of Pharmacology and Experimental Therapeutics. 192 (2): 310–8. PMID 1117418.
  3. Tessel RE; Rutledge CO (May 1976). "Specificity of release of biogenic amines from isolated rat brain tissue as a function of the meta substituent of N-ethylamphetamine derivatives". The Journal of Pharmacology and Experimental Therapeutics. 197 (2): 253–62. PMID 1271279.
  4. Tessel RE; Woods JH (May 1978). "meta Substituted N-ethylamphetamine self injection responding in the rhesus monkey: structure-activity relationships". The Journal of Pharmacology and Experimental Therapeutics. 205 (2): 274–81. PMID 417172.

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