Not to be confused with 2C-B (sometimes also referred to as "bromomescaline")
Clinical data
ATC code none
PubChem (CID) 16637783
ChemSpider 17574207 YesY
Chemical and physical data
Formula C11H16BrNO3
Molar mass 290.153 g/mol
3D model (Jmol) Interactive image

2-Bromomescaline (2-Br-M) is a derivative of the phenethylamine hallucinogen mescaline which has an unusual 2-bromo substitution.[1][2] It is an agonist for serotonin receptors, with a binding affinity of 215 nM at 5-HT1A, 513 nM at 5-HT2A and 379 nM at 5-HT2C, so while it is around ten times more tightly binding than mescaline at 5-HT1A and 5-HT2A receptors, it is over twenty times more potent at 5-HT2C.[3] Anecdotal reports in humans suggest it produces similar effects to mescaline, with around twice the potency but somewhat inferior effects.[4]

See also


  1. Pecherer B, Sunbury RC, Brossi A (1972). "Novel synthesis of aromatic methoxy and methylenedioxy-substituted 2,3,4,5-tetrahydro-1H-3-benzazepines". J Het Chem. 9 (3): 609–616.
  2. Alexander Shulgin; Tania Manning; Paul F Daley (2011). The Shulgin Index. Volume 1. Psychedelic Phenethylamines and Related Compounds. Transform Press. p. 280–281, 355. ISBN 978-0-9630096-3-0.
  3. Daniel Trachsel; David Lehmann; Christoph Enzensperger (2013). Phenethylamine Von der Struktur zur Funktion. Nachtschatten Verlag AG. p. 908–910. ISBN 978-3-03788-700-4.
  4. Dichloromescaline. Erowid.com, 2004
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