Spleen exonuclease

Spleen exonuclease
Identifiers
EC number 3.1.16.1
CAS number 9068-54-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Spleen exonuclease (EC 3.1.16.1, 3'-exonuclease, spleen phosphodiesterase, 3'-nucleotide phosphodiesterase, phosphodiesterase II) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 3'-phosphates (exonuclease type b)

This enzyme has a preference for single-stranded substrate.

References

  1. Bernardi, A.; Bernardi, G. (1971). "Spleen acid nuclease". In Boyer, P.D. The Enzymes. 4 (3rd ed.). New York: Academic Press. pp. 329–336.
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