Pyrrole-2-carboxylate decarboxylase

Pyrrole-2-carboxylate decarboxylase
Identifiers
EC number 4.1.1.93
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Pyrrole-2-carboxylate decarboxylase (EC 4.1.1.93) is an enzyme with systematic name pyrrole-2-carboxylate carboxy-lyase.[1][2][3] This enzyme catalyses the following chemical reaction

(1) pyrrole-2-carboxylate pyrrole + CO2
(2) pyrrole-2-carboxylate + H2O pyrrole + HCO3

The enzyme catalyses both the carboxylation and decarboxylation reactions.

References

  1. Wieser, M.; Fujii, N.; Yoshida, T.; Nagasawa, T. (1998). "Carbon dioxide fixation by reversible pyrrole-2-carboxylate decarboxylase from Bacillus megaterium PYR2910". Eur. J. Biochem. 257: 495–499. doi:10.1046/j.1432-1327.1998.2570495.x. PMID 9826198.
  2. Omura, H.; Wieser, M.; Nagasawa, T. (1998). "Pyrrole-2-carboxylate decarboxylase from Bacillus megaterium PYR2910, an organic-acid-requiring enzyme". Eur. J. Biochem. 253: 480–484. doi:10.1046/j.1432-1327.1998.2530480.x. PMID 9654100.
  3. Wieser, M.; Yoshida, T.; Nagasawa, T. (1998). "Microbial synthesis of pyrrole-2-carboxylate by Bacillus megaterium PYR2910". Tetrahedron Lett. 39: 4309–4310. doi:10.1016/s0040-4039(98)00718-7.
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