List of adverse effects of ribavirin
List of adverse effects of ribavirin by frequency.[1][2][3]
Very common (>10% frequency)
- Viral pharyngitis
- Anemia
- Neutropenia
- Appetite loss
- Weight loss
- Depression
- Anxiety
- Emotional lability
- Insomnia
- Headache
- Dizziness
- Dry mouth
- Concentration impaired
- Shortness of breath
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Hair loss
- Dry skin
- Itchiness
- Rash
- Joint aches and pains
- Muscle aches and pains
- Musculoskeletal pain
- Fatigue
- Rigors
- Fever
- Influenza-like illness
- Muscle weakness
- Irritability
Common (1-10% frequency)
- Hemolytic anemia
- Leukopenia
- Thrombocytopenia
- Lymphadenopathy
- Lymphopenia
- Hypothyroidism
- Hyperthyroidism
- Hyperglycemia
- Hyperuricemia
- Hypocalcemia
- Dehydration
- Increased appetite
- Palpitation
- Tachycardia
- Hypotension
- Hypertension
- Flushing
- Hepatomegaly
- Jaundice
- Hyperbilirubinemia
- Arthritis
- Back pain
- Muscle spasms
- Pain in extremity
- Micturition frequency
- Polyuria
- Urine abnormality
- Chest pain
- Chest discomfort
- Peripheral edema
- Malaise
- Feeling abnormal
- Thirst
- Cardiac murmur
- Neoplasm formation
- Sexual disturbances (including erectile dysfunction, prostatis, amenorrhea, etc.)
- Skin disturbances (including acne, eczema, psoriasis, etc.)
- Gastrointestinal disturbances (including mouth ulcers, indigestion, diarrhea, constipation, etc.)
- Upper respiratory tract disturbances (including nosebleeds, nasal/sinus congestion, etc.)
- Visual and hearing disturbances (including tinnitus, blurred vision, etc.)
- Neurologic disturbances (including memory loss, migraines, incoordination, sensory distortions, etc.)
- Psychiatric disturbances (including suicidal ideation and psychosis)
- Infections (including sinusitis, the flu, sepsis, UTIs, etc.)
Uncommon (0.1-1% frequency)
- Hypersensitivity
- Diabetes mellitus
- Hypertriglyceridemia
- Neuropathy
- Heart attack
- Mouth pain
- Pancreatitis
- Bone pain
- Facial edema
- Immediately life-threatening psychiatric disturbances, including suicide attempts and hallucinations
Rare (0.01-0.1% frequency)
- Pneumonia
- Sarcoidosis
- Rheumatoid arthritis
- Bipolar episode
- Seizures
- Serious eye complications
- Arrhythmia
- Cardiomyopathy
- Vasculitis
- Ischemic colitis
- Rhabdomyolysis
- Myositis
- Kidney failure or insufficiency
Very rare (<0.01% frequency)
- Aplastic anemia
- Suicide
- Stroke
- Polyneuropathy
- Encephalopathy
- Cardiac ischemia
- Life-threatening lung complications
- Ulcerative colitis
- Liver failure
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Erythema multiforme
- Nephrotic syndrome
Unknown frequency
- Pure red cell aplasia
- Idiopathic thrombocytopenic purpura
- Thrombotic thrombocytopenic purpura
- Mania
- Vogt-Koyanagi-Harada syndrome
- Systemic lupus erythematosus
- Vasculitis
- Hives
- Angioedema
- Bronchoconstriction
- Anaphylaxis
- Homicidal ideation
- Mental status change
- Facial palsy
- Mononeuropathies
- Pericardial effusion
- Pericarditis
- Periodontal disorder
References
- ↑ "PRODUCT INFORMATION REBETOL® (RIBAVIRIN) CAPSULES" (PDF). TGA eBusiness Services. Merck Sharp & Dohme (Australia) Pty Limited. 29 April 2013. Retrieved 23 February 2014.
- ↑ "COPEGUS (RIBAVIRIN) TABLET, FILM COATED [GENENTECH, INC]". DailyMed. Genentech, Inc. February 2013. Retrieved 23 February 2014.
- ↑ "Rebetol 200mg hard capsules - Summary of Product Characteristics". Merck Sharp & Dohme Limited. 27 January 2014. Retrieved 23 February 2014.
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