Homophthalic acid

Homophthalic acid
Names
IUPAC name
2-(Carboxymethyl)benzoic acid
Other names
α-Carboxy-o-toluic acid
Carboxyphenyl acetic acid
Identifiers
89-51-0
3D model (Jmol) Interactive image
ChemSpider 60010 YesY
ECHA InfoCard 100.001.740
Properties
C9H8O4
Molar mass 180.16 g·mol−1
Appearance Off-white to light yellow or pale green
Melting point 181 °C (358 °F; 454 K) [2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Homophthalic acid is a dicarboxylic acid with the formula C6H4(CO2H)CH2CO2H. It is a colorless solid. The compounds can be prepared by the Willgerodt reaction from 2-acetylbenzoic acid.[3]

One of the uses is in the preparation of the NSAID tesicam.

References

  1. Index
  2. Homophthalic Acid | C9H8O4 | Chemspider
  3. Schwenk, Erwin; Papa, Domenick "Preparation of aryl aliphatic acids by the modified Willgerodt reaction" Journal of Organic Chemistry (1946), 11, 798-802. doi:10.1021/jo01176a023


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