Diacylglycerol diphosphate phosphatase
| Diacylglycerol diphosphate phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.3.81 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Diacylglycerol diphosphate phosphatase (EC 3.1.3.81, DGPP phosphatase, DGPP phosphohydrolase, DPP1, DPPL1, DPPL2, PAP2, pyrophosphate phosphatase) is an enzyme with systematic name 1,2-diacyl-sn-glycerol 3-phosphate phosphohydrolase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- 1,2-diacyl-sn-glycerol 3-diphosphate + H2O 1,2-diacyl-sn-glycerol 3-phosphate + phosphate
The phosphatase activity of this enzyme is Mg2+-independent.
References
- ↑ Dillon, D.A.; Wu, W.I.; Riedel, B.; Wissing, J.B.; Dowhan, W.; Carman, G.M. (1996). "The Escherichia coli pgpB gene encodes for a diacylglycerol pyrophosphate phosphatase activity". J. Biol. Chem. 271: 30548–30553. doi:10.1074/jbc.271.48.30548. PMID 8940025.
- ↑ Dillon, D.A.; Chen, X.; Zeimetz, G.M.; Wu, W.I.; Waggoner, D.W.; Dewald, J.; Brindley, D.N.; Carman, G.M. (1997). "Mammalian Mg2+-independent phosphatidate phosphatase (PAP2) displays diacylglycerol pyrophosphate phosphatase activity". J. Biol. Chem. 272: 10361–10366. doi:10.1074/jbc.272.16.10361. PMID 9099673.
- ↑ Wu, W.I.; Liu, Y.; Riedel, B.; Wissing, J.B.; Fischl, A.S.; Carman, G.M. (1996). "Purification and characterization of diacylglycerol pyrophosphate phosphatase from Saccharomyces cerevisiae". J. Biol. Chem. 271: 1868–1876. doi:10.1074/jbc.271.4.1868. PMID 8567632.
- ↑ Oshiro, J.; Han, G.S.; Carman, G.M. (2003). "Diacylglycerol pyrophosphate phosphatase in Saccharomyces cerevisiae". Biochim. Biophys. Acta. 1635: 1–9. doi:10.1016/j.bbalip.2003.10.002. PMID 14642771.
- ↑ Carman, G.M. (1997). "Phosphatidate phosphatases and diacylglycerol pyrophosphate phosphatases in Saccharomyces cerevisiae and Escherichia coli". Biochim. Biophys. Acta. 1348: 45–55. doi:10.1016/s0005-2760(97)00095-7. PMID 9370315.
- ↑ Han, G.S.; Johnston, C.N.; Chen, X.; Athenstaedt, K.; Daum, G.; Carman, G.M. (2001). "Regulation of the Saccharomyces cerevisiae DPP1-encoded diacylglycerol pyrophosphate phosphatase by zinc". J. Biol. Chem. 276: 10126–10133. doi:10.1074/jbc.m011421200. PMID 11139591.
External links
- Diacylglycerol diphosphate phosphatase at the US National Library of Medicine Medical Subject Headings (MeSH)
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